Two sample MR report
LGALS2_Conventional Dendritic Cell against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | -0.1116373 | 0.9329500 | 0.9241822 |
| Weighted median | 3 | 0.0987876 | 0.0473098 | 0.0367890 |
| Inverse variance weighted | 3 | 0.0933527 | 0.0396859 | 0.0186582 |
| Simple mode | 3 | 0.1013853 | 0.0547761 | 0.2053972 |
| Weighted mode | 3 | 0.1014756 | 0.0550850 | 0.2067861 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0279249 | 1 | 0.8672854 |
| Inverse variance weighted | 0.0762904 | 2 | 0.9625732 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0971668 | 0.4418252 | 0.8621875 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 2.43e-05 | 0 | TRUE | 0.6408244 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
